Propagating waves in thalamus, cortex and the thalamocortical
system: experiments and models.
Lyle E. Muller and Alain Destexhe
J. Physiol. (Paris) 106: 222-238, 2012.
Propagating waves of activity have been recorded in many species,
in various brain states, brain areas, and under various stimulation
conditions. Here, we review the experimental literature on
propagating activity in thalamus and neocortex across various
levels of anesthesia and stimulation conditions. We also review
computational models of propagating waves in networks of thalamic
cells, cortical cells and of the thalamocortical system. Some
discrepancies between experiments can be explained by the "network
state", which differs vastly between anesthetized and awake
conditions. We introduce a network model displaying different
states and investigate their effect on the spatial structure of
self-sustained and externally driven activity. This approach is a
step towards understanding how the intrinsically-generated ongoing
activity of the network affects its ability to process and
propagate extrinsic input.
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